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eperisone 50 Background. Polypharmacy, defined as the concurrent use of multiple medications, significantly increases the risk of adverse drug reactions, drug–drug interactions, and specific geriatric syndromes such as falls, delirium, and cognitive impairment. 1 In Japan, the challenge of polypharmacy is exacerbated by an aging population and a high prevalence of chronic diseases. 2, 3 Adverse drug
